Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Dimethyl Sulfoxide → 6-(2-(5-(3-Chlorophenyl)-2-oxo-3-oxazolidinyl)propyl)-1,4-benzodioxan-2-yl-thiomethanol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Dimethyl Sulfoxide | HCID 679 | — |
| 반응물 | Water | HCID 962 | — |
| 반응물 | Potassium bisulfide | HCID 102109 | — |
| 반응물 | 3-Chloromethyl-6-(2-(5-(3-chloro-phenyl)-2-oxo-3-oxazolidinyl)propyl)-1,4-benzodioxane | HCID 54265284 | — |
| 생성물 | 6-(2-(5-(3-Chlorophenyl)-2-oxo-3-oxazolidinyl)propyl)-1,4-benzodioxan-2-yl-thiomethanol | HCID 18996366 | — |
반응 단계
One equivalent of product from Example 6, 2-isomer, and 2 equivalents of potassium hydrosulfide in dimethylsulfoxide is heated at 60° C. for 8 hours. The reaction mixture is poured into water, the precipitated product is collected and recrystallized from ethyl alcohol to give 6-(2-(5-(3-chlorophenyl)-2-oxo-3-oxazolidinyl)propyl)-1,4-benzodioxan-2-yl-thiomethanol.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05482971 |
| 출처 데이터셋 | uspto-grants-1996_01 |
| ORD ID | ord-27f2f83ee43e4e299ab0c6d381927da5 |
| 출처 메모 | uspto-grants-1996_01 |