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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 375696생성일: 2026년 10월 24일

Sodium Cyanide → 2-(3-(Hydroxymethyl)oxetan-3-yl)acetonitrile

https://huagongshe.com/ko/reaction/375696

반응식

참여 물질

역할이름HCID투입량
반응물Sodium CyanideHCID 8929—
반응물[3-(Bromomethyl)oxetan-3-yl]methanolHCID 529264—
용매EthanolHCID 702—
생성물2-(3-(Hydroxymethyl)oxetan-3-yl)acetonitrileHCID 11007909—

반응 단계

A solution of 42 g (0.23 mol) of [3-(bromomethyl)oxetan-3-yl] methanol (produced according to Example 1) in 420 ml of ethanol was refluxed with 13 g (0.265 mol) of sodium cyanide for 18 hours. After cooling to room temperature, the precipitated sodium bromide was filtered off and the filtrate concentrated by evaporation. The residue was distilled at 0.4 torr. The yield of product as a colorless oil was 16 g (54 percent). The boiling point of the product was 107° C./0.4 torr. Other data concerning the product was:

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US05486622
출처 데이터셋uspto-grants-1996_01
ORD IDord-3fcf3ec291cc42e19566979fd5a4612d
출처 메모uspto-grants-1996_01