참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Phenyl isocyanate | HCID 7672 | — |
| 반응물 | 5-Amino-1-phenyl-1H-pyrazole-4-carbonitrile | HCID 79256 | — |
| 반응물 | Potassium tert-butoxide | HCID 23665647 | — |
| 용매 | Toluene | HCID 1140 | — |
| 생성물 | 1-Phenyl-4-cyano-5-(phenylureido)-pyrazole | HCID 18993713 | 96% |
반응 단계
9.0 g (80 mmol) of potassium tert-butylate and 8.7 ml (80 mmol) of phenyl isocyanate were added to a solution of 5.52 g (30 mmol) of 1-phenyl-4-cyano-5-aminopyrazole in 100 ml of toluene. The mixture was heated for 15 hours at 80° C. and then cooled, the insoluble constituents were separated off and the resulting solution was acidified with acetic acid, the product crystallizing out. Yield: 96%.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US05486618 |
|---|
| 출처 데이터셋 | uspto-grants-1996_01 |
|---|
| ORD ID | ord-d3008fed65aa48ba88f258b2fe528189 |
|---|
| 출처 메모 | uspto-grants-1996_01 |
|---|
