Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Nipecotic Acid → 1-((Benzyloxy)carbonyl)piperidine-3-carboxylic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Nipecotic Acid | HCID 4498 | — |
| 반응물 | Benzyl chloroformate | HCID 10387 | — |
| 생성물 | 1-((Benzyloxy)carbonyl)piperidine-3-carboxylic acid | HCID 234339 | — |
반응 단계
By substantially following the procedures of Example 1,A, 25.0 g (194 mmol) of nipecotic acid was protected with benzylchloroformate under basic conditions to afford 18.0 g (68 mmol; 35%) of analytically pure N-Cbz-nipecotic acid as a white solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05488037 |
| 출처 데이터셋 | uspto-grants-1996_01 |
| ORD ID | ord-ef87f616f49c4ab4b0a9b1b7e0b2a433 |
| 출처 메모 | uspto-grants-1996_01 |