2-(7-bromo-5-methyl-1H-indol-3-yl)ethanamine hydrochloride → 4-Fluoro-5-methyltryptamine hydrochloride

반응식

[ClH:1].[CH3:2][C:3]1[CH:14]=[C:13]2[C:6]([NH:7][CH:8]=[C:9]2[CH2:10][CH2:11][NH2:12])=[C:5](Br)[CH:4]=1.Cl.[F:17]C1C=C(NN)C=CC=1C>>[ClH:1].[F:17][C:14]1[C:3]([CH3:2])=[CH:4][CH:5]=[C:6]2[C:13]=1[C:9]([CH2:10][CH2:11][NH2:12])=[CH:8][NH:7]2

참가 물질

반응물 2

HCID 164953872-(7-bromo-5-methyl-1H-indol-3-yl)ethanamine hydrochloride

HCID 44557932(3-Fluoro-4-methylphenyl)hydrazine hydrochloride

생성물 1

HCID 187022534-Fluoro-5-methyltryptamine hydrochloride

실험 절차

4-Fluoro-5-methyltryptamine hydrochloride was prepared (2.20 g) as described for 5-methyl-7-bromotryptamine hydrochloride in Example 7, except using 3-fluoro-4-methylphenylhydrazine hydrochloride (6.00 g) as starting material. ##STR50##

출처 및 근거

ORD 기록: ord-9b768fcb8a794b1aa950eb417dc27a00
출처 데이터셋: uspto-grants-1996_01
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US05488053

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