Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 376438생성일: 2026년 10월 26일
Ethylmorpholine → 3-Hydroxypyridine-2-carboxylic acid N-(((1-dodecyloxy)carbonyl)methyl)amide
https://huagongshe.com/reaction/376438
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Ethylmorpholine | HCID 7525 | — |
| 반응물 | 3-Hydroxypicolinic Acid | HCID 13401 | — |
| 반응물 | 1-Hydroxybenzotriazole | HCID 75771 | — |
| 반응물 | N-cyclohexyl-N'-(2-morpholinoethyl)-carbodiimide methyl-p-toluenesulfonate | HCID 9954069 | — |
| 반응물 | Glycine 1-dodecyl ester tosylate | HCID 15435490 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | 3-Hydroxypyridine-2-carboxylic acid N-(((1-dodecyloxy)carbonyl)methyl)amide | HCID 9842011 | — |
반응 단계
7 g (50 mmol) of 3-hydroxypyridine-2-carboxylic acid were suspended in 800 ml of anhydrous dichloromethane and treated with 7.5 g (55 mmol) of 1-hydroxy-1H-benzotriazole, 19.2 ml (150 mmol) of N-ethylmorpholine, 21.2 g (50 mmol) of N-cyclohexyl-N'-(2-morpholinoethyl)carbodiimide methyl-p-toluenesulfonate (CMC) and 20.8 g (50 mmol) of glycine 1-dodecyl ester tosylate and the mixture was stirred at 20° C. for 50 h.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US06020350 |
|---|
| 출처 데이터셋 | uspto-grants-2000_02 |
|---|
| ORD ID | ord-015e862b3cb0448ab6bfcf1d5e1d4c92 |
|---|
| 출처 메모 | uspto-grants-2000_02 |
|---|
