Diethylamine → N,N-Diethyl-2,5-bis(trifluoromethyl)benzamide

반응식

[F:1][C:2]([F:17])([F:16])[C:3]1[CH:11]=[CH:10][C:9]([C:12]([F:15])([F:14])[F:13])=[CH:8][C:4]=1[C:5](Cl)=[O:6].[CH2:18]([NH:20][CH2:21][CH3:22])[CH3:19]>>[CH2:18]([N:20]([CH2:21][CH3:22])[C:5](=[O:6])[C:4]1[CH:8]=[C:9]([C:12]([F:15])([F:14])[F:13])[CH:10]=[CH:11][C:3]=1[C:2]([F:17])([F:16])[F:1])[CH3:19]

참가 물질

반응물 2

HCID 8021Diethylamine

HCID 27378122,5-Bis(trifluoromethyl)benzoyl chloride

생성물 1

HCID 15832108N,N-Diethyl-2,5-bis(trifluoromethyl)benzamide

실험 절차

N,N-Diethyl-2,5-bis(trifluoromethyl)benzamide was prepared from 2,5-bis(trifluoromethyl)benzoyl chloride and diethylamine according to General Method E1. The desired intermediate was isolated in quantitative yield (11.3 g) without additional purification.

출처 및 근거

ORD 기록: ord-1a779ae58bb44501ad3e0c93506808b1
출처 데이터셋: uspto-grants-2000_02
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: USRE036562

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