Chloride → Salicyloyl chloride

HRID 376784

반응식

HRID 376784 반응식
[C:1]([OH:10])(=O)[C:2]1[C:3](=[CH:5][CH:6]=[CH:7][CH:8]=1)[OH:4].[Cl-:11]>N1C=CC=CC=1>[C:1]([Cl:11])(=[O:10])[C:2]1[C:3](=[CH:5][CH:6]=[CH:7][CH:8]=1)[OH:4]

참가 물질

4

반응물 2

HCID 312ChlorideHCID 338Salicylic Acid

생성물 1

HCID 74041Salicyloyl chloride

시약·촉매·용매 1

HCID 1049Pyridine촉매

실험 절차

In the first step, salicylic acid is mixed with thionyl (or oxalyl) halide, most preferably chloride, (molar ratio in the general range of from 1:1 to 2:1) in an anhydrous, typically non-polar, solvent, in the presence of pyridine catalyst, at a temperature of from 20 to 45° C. for 0.5-2 hours. At the end of this reaction, salicylic acid chloride id obtained. Optionally, the solvent is distilled at least partially.

후처리

  1. customAt the end of this reaction

출처 및 근거

ORD 기록
ord-ba041bf2371343febef57cfb21763815
출처 데이터셋
uspto-grants-2000_02
특허 번호
US06022548

연결된 노트

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