Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → 3-(4-nitrophenyl)-2-hydroxy-N-(2-aminoethyl)propionamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | Nitric Acid | HCID 944 | — |
| 반응물 | Atrolactic acid | HCID 1303 | — |
| 반응물 | Ethylenediamine | HCID 3301 | — |
| 반응물 | Methyl-p-nitrophenyl lactate | HCID 56998982 | — |
| 용매 | Methanol | HCID 887 | — |
| 용매 | Sulfuric Acid | HCID 1118 | — |
| 생성물 | 3-(4-nitrophenyl)-2-hydroxy-N-(2-aminoethyl)propionamide | HCID 19360733 | — |
반응 단계
Phenyl-lactic acid (available from Aldrich Chemical Co., Milwaukee, Wis.) is nitrated with nitric acid in sulfuric acid. P-nitrophenyl lactic acid is esterified with methanol and gaseous hydrochloric acid. Methyl-p-nitrophenyl lactate is condensed with ethylene diamine to provide the amide adduct, 3-(4-nitrophenyl)-2-hydroxy-N-(2-aminoethyl)propionamide.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06022966 |
| 출처 데이터셋 | uspto-grants-2000_02 |
| ORD ID | ord-1457048d56e0407caf57f36a180c5d16 |
| 출처 메모 | uspto-grants-2000_02 |