Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Acetic Acid → 6-Benzyloxy-a-methyl-1,2,3,4-tetrahydrocarbazole-2-acetic acid ethyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Acetic Acid | HCID 176 | — |
| 반응물 | (4-(Benzyloxy)phenyl)hydrazine monohydrochloride | HCID 3016725 | — |
| 반응물 | a-Methyl-3-oxocyclohexane acetic acid | HCID 57367081 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 6-Benzyloxy-a-methyl-1,2,3,4-tetrahydrocarbazole-2-acetic acid ethyl ester | HCID 53823360 | — |
반응 단계
A mixture containing 4-benzyloxyphenylhydrazine hydrochloride (37.0 g, 0.148 mol), a-methyl-3-oxocyclohexane acetic acid (40.0 g, 0.235 mol), glacial acetic acid (650 mL) and H2O (100 mL) is stirred at room temperature under a nitrogen atmosphere for 2.5 hours. The mixture is then refluxed for 20 minutes, cooled and poured into 200 mL of ice/H2O. The precipitate is filtered to give 80 g of red colored crude product.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05420289 |
| 출처 데이터셋 | uspto-grants-1995_05 |
| ORD ID | ord-4b025cac112b49168dfc24a172f3c62e |
| 출처 메모 | uspto-grants-1995_05 |