Diphenyl Ether → 4-phenoxybenzenesulfonic Acid
반응식
[C:1]1([O:7][C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.Cl[S:15]([OH:18])(=[O:17])=[O:16]>C(Cl)Cl>[O:7]([C:1]1[CH:2]=[CH:3][C:4]([S:15]([OH:18])(=[O:17])=[O:16])=[CH:5][CH:6]=1)[C:8]1[CH:9]=[CH:10][CH:11]=[CH:12][CH:13]=1참가 물질
4
반응 조건
- 온도
- 0 °C
실험 절차
To a solution of diphenyl ether 1a (2.00 g, 11.8 mmol) in dry CH2Cl2 (30 mL) under an argon atmosphere at 0° C., was added chlorosulphonic acid (0.80 mL, 11.8 mmol). The reaction mixture was stirred for 2 h at 0° C. The solvent was evaporated at room temperature and the residue dried overnight under vacuum to give the corresponding 4-phenoxybenzenesulphonic acid (2a) as pink oil. Compound 2a was used for the next reaction without further work-up.
후처리
- customThe solvent was evaporated at room temperature
- customthe residue dried overnight under vacuum
출처 및 근거
- ORD 기록
- ord-5296f3dd0d9040088cd436703ba7d23f
- 출처 데이터셋
- uspto-grants-2013_09
- 특허 번호
- US08524194B2
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