Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Dimethylamine → 9-Ethyl-7-methyl-4-(dimethylamino)-2-(methylthio)imidazo[5,1-h]pteridin-6(5H)-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Dimethylamine | HCID 674 | — |
| 반응물 | Stannous Chloride | HCID 24479 | — |
| 반응물 | 1,1'-Carbonyldiimidazole | HCID 68263 | — |
| 반응물 | 4,6-Dichloro-2-(methylthio)-5-nitropyrimidine | HCID 11345458 | — |
| 반응물 | HCID 178437635 | HCID 178437635 | — |
| 생성물 | 9-Ethyl-7-methyl-4-(dimethylamino)-2-(methylthio)imidazo[5,1-h]pteridin-6(5H)-one | HCID 19358871 | — |
반응 단계
Prepared by treatment of 4,6-dichloro-5-nitro-2-(methylthio)pyrimidine with dimethylamine, followed by reaction with 2-ethyl-4-methylimidazole, reduction with tin (II) chloride, and cyclization with carbonyidiimidazole.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06025489 |
| 출처 데이터셋 | uspto-grants-2000_02 |
| ORD ID | ord-be130903f6a74ca6833ade33de7b4594 |
| 출처 메모 | uspto-grants-2000_02 |