Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrazine hydrate (1:1) → 6-hydrazino-1-isobutyl-3-methyl-2,4(1H,3H)-pyrimidinedione
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrazine hydrate (1:1) | HCID 24654 | — |
| 반응물 | 6-Chloro-1-isobutyl-3-methylpyrimidine-2,4(1H,3H)-dione | HCID 5282566 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 6-hydrazino-1-isobutyl-3-methyl-2,4(1H,3H)-pyrimidinedione | HCID 19356084 | — |
반응 단계
Hydrazine hydrate (6.5 ml) was added to a solution of 6-chloro-3-methyl-1-(2-methylpropyl)pyrimidine-2,4[1H,3H]-dione (10.0 g) in ethanol (40 ml). The mixture was heated at reflux for 5 hours, cooled to room temperature and then evaporated under reduced pressure. The residue was recrystallised from ethanol to give the subtitle compound (8.8 g).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06028074 |
| 출처 데이터셋 | uspto-grants-2000_02 |
| ORD ID | ord-0babe5e48b794874b958f26057a9078b |
| 출처 메모 | uspto-grants-2000_02 |