1-(3-Isopropoxyphenyl)piperazine → 1-[(2-Methoxyquinolin-3-yl)aminocarbonyl]-4-(3-isopropoxyphenyl)piperazine

HRID 377878노트

반응식

HRID 377878 반응식
[CH3:1][O:2][C:3]1[C:12]([NH:13][C:14](=[O:22])OC2C=CC=CC=2)=[CH:11][C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[N:4]=1.[CH:23]([O:26][C:27]1[CH:28]=[C:29]([N:33]2[CH2:38][CH2:37][NH:36][CH2:35][CH2:34]2)[CH:30]=[CH:31][CH:32]=1)([CH3:25])[CH3:24]>>[CH3:1][O:2][C:3]1[C:12]([NH:13][C:14]([N:36]2[CH2:35][CH2:34][N:33]([C:29]3[CH:30]=[CH:31][CH:32]=[C:27]([O:26][CH:23]([CH3:25])[CH3:24])[CH:28]=3)[CH2:38][CH2:37]2)=[O:22])=[CH:11][C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[N:4]=1

참가 물질

3

반응물 2

HCID 186690581-(3-Isopropoxyphenyl)piperazineHCID 19356985Phenyl N-(2-methoxyquinolin-3-yl)carbamate

생성물 1

HCID 193569721-[(2-Methoxyquinolin-3-yl)aminocarbonyl]-4-(3-isopropoxyphenyl)piperazine수율 93%

실험 절차

Phenyl N-(2-methoxyquinolin-3-yl)carbamate and 1-(3-isopropoxyphenyl)piperazine were reacted by the same way with the example 81 to obtain the titled compound.

출처 및 근거

ORD 기록
ord-3a19eaf5e9734c30a030c0a5bc7bf02c
출처 데이터셋
uspto-grants-2000_02
특허 번호
US06028195

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