1-(3,5-Dichlorophenyl)piperazine → 1-[(2-Methoxyquinolin-3-yl)aminothiocarbonyl]-4-(3,5-dichlorophenyl)piperazine

HRID 377890

반응식

HRID 377890 반응식
[CH3:1][O:2][C:3]1[C:12]([NH:13][C:14](=[S:22])OC2C=CC=CC=2)=[CH:11][C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[N:4]=1.[Cl:23][C:24]1[CH:25]=[C:26]([N:31]2[CH2:36][CH2:35][NH:34][CH2:33][CH2:32]2)[CH:27]=[C:28]([Cl:30])[CH:29]=1>>[CH3:1][O:2][C:3]1[C:12]([NH:13][C:14]([N:34]2[CH2:33][CH2:32][N:31]([C:26]3[CH:25]=[C:24]([Cl:23])[CH:29]=[C:28]([Cl:30])[CH:27]=3)[CH2:36][CH2:35]2)=[S:22])=[CH:11][C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[N:4]=1

참가 물질

3

반응물 2

HCID 27360671-(3,5-Dichlorophenyl)piperazineHCID 54112042Phenyl N-(2-methoxyquinolin-3-yl)thiocarbamate

생성물 1

HCID 540425771-[(2-Methoxyquinolin-3-yl)aminothiocarbonyl]-4-(3,5-dichlorophenyl)piperazine수율 62%

실험 절차

Phenyl N-(2-methoxyquinolin-3-yl)thiocarbamate and 1-(3,5-dichlorophenyl)piperazine were reacted by the same way with the example 109 to obtain the titled compound.

출처 및 근거

ORD 기록
ord-dbb5d5672271449d976bf1032f67d1e4
출처 데이터셋
uspto-grants-2000_02
특허 번호
US06028195

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