1-(2-Chlorophenyl)piperazine → 1-[(2-Methylquinolin-3-yl)aminocarbonyl]-4-(2-chlorophenyl)piperazine

HRID 377896노트

반응식

HRID 377896 반응식
[CH3:1][C:2]1[C:11]([NH:12][C:13](=[O:21])OC2C=CC=CC=2)=[CH:10][C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[N:3]=1.[Cl:22][C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][C:24]=1[N:29]1[CH2:34][CH2:33][NH:32][CH2:31][CH2:30]1>>[CH3:1][C:2]1[C:11]([NH:12][C:13]([N:32]2[CH2:31][CH2:30][N:29]([C:24]3[CH:25]=[CH:26][CH:27]=[CH:28][C:23]=3[Cl:22])[CH2:34][CH2:33]2)=[O:21])=[CH:10][C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[N:3]=1

참가 물질

3

반응물 2

HCID 4156281-(2-Chlorophenyl)piperazineHCID 19356949Phenyl N-(2-methylquinolin-3-yl)carbamate

생성물 1

HCID 193570981-[(2-Methylquinolin-3-yl)aminocarbonyl]-4-(2-chlorophenyl)piperazine수율 72%

실험 절차

Phenyl N-(2-methylquinolin-3-yl)carbamate and 1-(2-chlorophenyl)piperazine were reacted by the same way with the example 114 to obtain the titled compound.

출처 및 근거

ORD 기록
ord-03076cb5f1a04f119c83510392869e64
출처 데이터셋
uspto-grants-2000_02
특허 번호
US06028195

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