Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Bromophenylhydrazine hydrochloride → 9-bromo-3,4,5,6-tetrahydro-1H-2,5-ethanoazepino[4,3-b]indole
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Bromophenylhydrazine hydrochloride | HCID 12157 | — |
| 반응물 | 1-Azabicyclo[3.2.2]nonan-4-one | HCID 6420307 | — |
| 생성물 | 9-bromo-3,4,5,6-tetrahydro-1H-2,5-ethanoazepino[4,3-b]indole | HCID 67238975 | — |
반응 단계
4-Bromophenylhydrazine hydrochloride (4.33 g, 19.37 mmol; Aldrich) and the product of Example 1A (2.70 g, 19.37 mmol) were processed as described in Example 1B to provide the title compound: 1H NMR (300 MHz, methanol-d4) δ ppm 2.14-2.36 (m, 4 H), 3.17-3.25 (m, 1 H), 3.33-3.45 (m, 2 H), 3.45-3.65 (m, 2 H), 4.54 (s, 2 H), 7.18 (dd, J=8.8, 1.8 Hz, 1 H), 7.24 (d, J=9.1 Hz, 1 H), 7.51 (d, J=2.4 Hz, 1 H); MS (DCI) m/z 291/293 (M+H)+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08524703B2 |
| 출처 데이터셋 | uspto-grants-2013_09 |
| ORD ID | ord-c64b66b49ab94e219653701ce085ce8f |
| 출처 메모 | uspto-grants-2013_09 |