Phenyl N-(4,5-dimethyl-2-methoxyphenyl)carbamate → 1-[(4,5-Dimethyl-2-methoxyphenyl)aminocarbonyl]-4-(2-methoxy-5-phenylphenyl)piperazine

HRID 377920노트

반응식

HRID 377920 반응식
[CH3:1][C:2]1[C:7]([CH3:8])=[CH:6][C:5]([NH:9][C:10](=[O:18])OC2C=CC=CC=2)=[C:4]([O:19][CH3:20])[CH:3]=1.[CH3:21][O:22][C:23]1[CH:28]=[CH:27][C:26]([C:29]2[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=2)=[CH:25][C:24]=1[N:35]1[CH2:40][CH2:39][NH:38][CH2:37][CH2:36]1>>[CH3:1][C:2]1[C:7]([CH3:8])=[CH:6][C:5]([NH:9][C:10]([N:38]2[CH2:37][CH2:36][N:35]([C:24]3[CH:25]=[C:26]([C:29]4[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=4)[CH:27]=[CH:28][C:23]=3[O:22][CH3:21])[CH2:40][CH2:39]2)=[O:18])=[C:4]([O:19][CH3:20])[CH:3]=1

참가 물질

3

반응물 2

HCID 19357180Phenyl N-(4,5-dimethyl-2-methoxyphenyl)carbamateHCID 193571831-(2-Methoxy-5-phenylphenyl)piperazine

생성물 1

HCID 193571451-[(4,5-Dimethyl-2-methoxyphenyl)aminocarbonyl]-4-(2-methoxy-5-phenylphenyl)piperazine수율 91%

실험 절차

Phenyl N-(4,5-dimethyl-2-methoxyphenyl)carbamate and 1-(2-methoxy-5-phenylphenyl)piperazine were reacted by the same way with the example 170 to obtain the titled compound.

출처 및 근거

ORD 기록
ord-6c9a0299650340329d92559159cb08aa
출처 데이터셋
uspto-grants-2000_02
특허 번호
US06028195

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