Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
t-butoxycarbonyl-D-methionylglycyl-N-(6-methoxy-6-oxohexyl)-L-phenylalaninamide → D-methionylglycyl-N-(6-methoxy-6-oxohexyl)-L-phenylalaninamide monohydrochloride hemihydrate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | t-butoxycarbonyl-D-methionylglycyl-N-(6-methoxy-6-oxohexyl)-L-phenylalaninamide | HCID 13385843 | — |
| 반응물 | 1,4-Dioxane hydrochloride | HCID 20443148 | — |
| 용매 | 1,4-Dioxane | HCID 31275 | — |
| 생성물 | D-methionylglycyl-N-(6-methoxy-6-oxohexyl)-L-phenylalaninamide monohydrochloride hemihydrate | HCID 131714086 | — |
반응 단계
The title compound of Example 10 (12.0 g) was dissolved in 50 ml of dioxane to which was added 50 ml of 6M hydrogen chloride/dioxane. After about one hour, the volatiles were removed in vacuo and the residue triturated thoroughly with diethyl ether. The title compound (10.9 g) was collected as an analytically pure hydrochloride hemihydrate.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04722922 |
| 출처 데이터셋 | uspto-grants-1988_02 |
| ORD ID | ord-5cde0d6b47b04ae18f76dd684a697a17 |
| 출처 메모 | uspto-grants-1988_02 |