참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Dimethylformamide diethylacetal | HCID 70913 | — |
| 반응물 | Ethyl 2-(6-chloropyridin-3-yl)acetate | HCID 15661146 | — |
| 생성물 | Ethyl 2-(6-chloropyridin-3-yl)-3-(dimethylamino)acrylate | HCID 72537728 | — |
반응 단계
3.99 g (20.0 mmol) of the compound from Example 1A are dissolved in 13.7 ml of dimethylformamide diethyl acetal, and the mixture is stirred with microwave irradiation at 90° C. for 30 min. The mixture is then concentrated on a rotary evaporator, and the residue is chromatographed on silica gel 60 (mobile phase: dichloromethane→dichloromethane/methanol 20:1).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US08524699B2 |
|---|
| 출처 데이터셋 | uspto-grants-2013_09 |
|---|
| ORD ID | ord-16cc391b4b8f4a33be01b15eb6e4129f |
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| 출처 메모 | uspto-grants-2013_09 |
|---|
