Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methyl Methanesulfonate → 4-Phenylamino-2-amino-1,6-dimethylpyrimidinium methanesulfonate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methyl Methanesulfonate | HCID 4156 | — |
| 반응물 | 2-Amino-4-phenylamino-6-methylpyrimidine | HCID 608203 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 4-Phenylamino-2-amino-1,6-dimethylpyrimidinium methanesulfonate | HCID 22394029 | — |
반응 단계
Compound No. 46. A suspension of 4-phenylamino-2-amino-6-methylpyrimidine, Compound No. 45, (0.25 g) in ethanol (4 mL) was treated with methyl methanesulfonate (0.090 g) and heated at reflux for 5 days. Additional methyl methanesulfonate (0.090 g) was added and the mixture refluxed another 2 days. Concentration and recrystallization from a mixture of methanol, ethyl acetate, and tert-butyl ethyl ether gave 0.10 g of 4-phenylamino-2-amino-1,6-dimethylpyrimidinium methanesulfonate.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06297253B1 |
| 출처 데이터셋 | uspto-grants-2001_10 |
| ORD ID | ord-907ab1d159414431b2120ad2cb4c0668 |
| 출처 메모 | uspto-grants-2001_10 |