Ammonium Chloride → HCID 178507487, 화합물

HRID 378956노트

반응식

HRID 378956 반응식
[NH2:1][C:2]1[CH:9]=[CH:8][CH:7]=[CH:6][C:3]=1[C:4]#[N:5].[N-:10]=[N+:11]=[N-:12].[Na+].[Cl-].[NH4+]>CN(C)C=O>[NH2:1][C:2]1[CH:9]=[CH:8][CH:7]=[CH:6][C:3]=1[C:4]1[NH:12][N:11]=[N:10][N:5]=1

참가 물질

5

반응물 3

HCID 25517Ammonium ChlorideHCID 33557Sodium AzideHCID 729132-Aminobenzonitrile

생성물 1

HCID 178507487HCID 178507487, 화합물수율 65.2%

시약·촉매·용매 1

HCID 6228Dimethylformamide용매

반응 조건

온도
120 °C

실험 절차

2-Aminobenzonitrile (9.44 g, 80 mmol), sodium azide, (6.24 g, 0.1 mol), ammonium chloride (5.12 g, 0.1 mol) and dimethylformamide (50 mL) were mixed and heated at 120° C. overnight. The solvent was evaporated and the residue taken up in water. The crude product was isolated by filtration and recrystallised from water. A yield of 8.4 g of pure product was obtained

후처리

  1. customThe solvent was evaporated
  2. customThe crude product was isolated by filtration
  3. customrecrystallised from water

출처 및 근거

ORD 기록
ord-71beed2bbdfa4374ae9afd74b679ef2e
출처 데이터셋
uspto-grants-2001_10
특허 번호
US06297261B1

반응 노트

불러오는 중…