Acetic Acid → Methylamine

HRID 378976노트

반응식

HRID 378976 반응식
[C:1]1([CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][O:12][C:13]2[CH:20]=[CH:19][C:16]([CH:17]=O)=[CH:15][C:14]=2[O:21][CH3:22])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.C(O)C.C(O)(=O)C.[N+:30]([CH3:33])([O-:32])=[O:31]>CO>[CH3:33][NH2:30].[C:1]1([CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][O:12][C:13]2[CH:20]=[CH:19][C:16]([CH:17]=[CH:33][N+:30]([O-:32])=[O:31])=[CH:15][C:14]=2[O:21][CH3:22])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

참가 물질

7

반응물 4

HCID 176Acetic AcidHCID 702EthanolHCID 6375NitromethaneHCID 216972874-(5-Phenylpentyloxy)-3-methoxy-benzaldehyde

생성물 2

HCID 6329MethylamineHCID 541505081-(5-Phenylpentyloxy)-2-methoxy-4-(2-nitro-vinyl)-benzene

시약·촉매·용매 1

HCID 887Methanol용매

실험 절차

Operating analogously to example 2 using 4-(5-phenylpentyloxy)-3-methoxy-benzaldehyde (21 g, 73.4 mmoles), obtained as described in example 21, in methanol (86 ml), 8.03M methylamine in ethanol (1.92 ml, 15.4 mmoles), acetic acid (0.88 ml, 15.4 mmoles) and nitromethane (4.34 ml, 80.7 mmoles) 20 g of the title product were obtained (yield: 80%).

후처리

  1. customobtained

출처 및 근거

ORD 기록
ord-f98f33e9f9bd44ef92de8a8a996bd8e0
출처 데이터셋
uspto-grants-2001_10
특허 번호
US06297257B1

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