Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-Bromo-3-chloropropane → 4-Chlorobenzyl-4-(3-chloropropyl)piperazine dihydrochloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-Bromo-3-chloropropane | HCID 8006 | — |
| 반응물 | Potassium Hydroxide | HCID 14797 | — |
| 반응물 | 4-Chlorobenzylpiperazine | HCID 134826 | — |
| 용매 | Dimethyl Sulfoxide | HCID 679 | — |
| 생성물 | 4-Chlorobenzyl-4-(3-chloropropyl)piperazine dihydrochloride | HCID 20153189 | 74% |
반응 단계
Utilizing the procedure described in Example 1(a), 20.0 g of 1-(4-chlorobenzyl)piperazine, 100 ml of dimethyl sulfoxide, 15.0 g of potassium hydroxide and 15.0 of 1-bromo-3-chloropropane yielded 25.1 g (74% of theory) of 1-(4-chlorobenzyl)-4-(3-chloropropyl)piperazine dihydrochloride as a white crystalline solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04722926 |
| 출처 데이터셋 | uspto-grants-1988_02 |
| ORD ID | ord-2696e8dc20db40a1b56b86bc942054c8 |
| 출처 메모 | uspto-grants-1988_02 |