Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Potassium Carbonate → 3-(2-Chloro-5-pyridylmethyl)-2-(nitroimino)thiazolidine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | 2-Chloro-5-(chloromethyl)pyridine | HCID 155479 | — |
| 반응물 | 2-Nitroiminothiazolidine | HCID 136247439 | — |
| 용매 | Acetonitrile | HCID 6342 | — |
| 생성물 | 3-(2-Chloro-5-pyridylmethyl)-2-(nitroimino)thiazolidine | HCID 53880263 | — |
반응 단계
A mixture of 2.9 g of 2-nitroiminothiazolidine, 2.9 g of anhydrous potassium carbonate, 3.2 g of 2-chloro-5-pyridylmethylchloride and 50 ml of acetonitrile was refluxed for 5 hours with vigorously stirring. After the reaction, most of the acetonitrile was removed by distillation and water was added to the residue. As the solid product was separated, it was collected by filtration. The crude material was recrystallized from ethanol to give desired 3-(2-chloro-5-pyridylmethyl)-2-(nitroimino)thiazolidine.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06297374B1 |
| 출처 데이터셋 | uspto-grants-2001_10 |
| ORD ID | ord-c5e117cc5b2245c587c08400dffad131 |
| 출처 메모 | uspto-grants-2001_10 |