4-(1-(4-fluorobenzyl)-1H-benzimidazole-2-carbonyl)piperidine → N-Methyl-N-(4-(4-(1-(4-fluorobenzyl)-1H-benzimidazole-2-carbonyl)piperidin-1-yl)-2-(3,4-dimethoxyphenyl)butyl)benzamide
반응식
[CH3:1][N:2]([CH2:11][CH:12]([C:19]1[CH:24]=[CH:23][C:22]([O:25][CH3:26])=[C:21]([O:27][CH3:28])[CH:20]=1)[CH2:13][CH2:14]S(C)(=O)=O)[C:3](=[O:10])[C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1.[F:29][C:30]1[CH:53]=[CH:52][C:33]([CH2:34][N:35]2[C:39]3[CH:40]=[CH:41][CH:42]=[CH:43][C:38]=3[N:37]=[C:36]2[C:44]([CH:46]2[CH2:51][CH2:50][NH:49][CH2:48][CH2:47]2)=[O:45])=[CH:32][CH:31]=1>>[CH3:1][N:2]([CH2:11][CH:12]([C:19]1[CH:24]=[CH:23][C:22]([O:25][CH3:26])=[C:21]([O:27][CH3:28])[CH:20]=1)[CH2:13][CH2:14][N:49]1[CH2:50][CH2:51][CH:46]([C:44]([C:36]2[N:35]([CH2:34][C:33]3[CH:32]=[CH:31][C:30]([F:29])=[CH:53][CH:52]=3)[C:39]3[CH:40]=[CH:41][CH:42]=[CH:43][C:38]=3[N:37]=2)=[O:45])[CH2:47][CH2:48]1)[C:3](=[O:10])[C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1참가 물질
3
실험 절차
Prepare by the method of Example 1.7 using N-methyl-N-(2-(3,4-dimethoxyphenyl)-4-methanesulfonylbutyl)benzamide and 4-(1-(4-fluorobenzyl)-1H-benzimidazole-2-carbonyl)piperidine to give the title compound.
출처 및 근거
- ORD 기록
- ord-feef688704a84ce1a812f58cc45a3db8