Oxalyl chloride → 2-methoxy-5-(4H-triazol-4-yl)benzoyl chloride

HRID 379485노트

반응식

HRID 379485 반응식
[CH3:1][O:2][C:3]1[CH:11]=[CH:10][C:9]([CH:12]2[CH:16]=[N:15][N:14]=[N:13]2)=[CH:8][C:4]=1[C:5](O)=[O:6].C(Cl)(=O)C([Cl:20])=O>CN(C)C=O.ClCCl>[CH3:1][O:2][C:3]1[CH:11]=[CH:10][C:9]([CH:12]2[CH:16]=[N:15][N:14]=[N:13]2)=[CH:8][C:4]=1[C:5]([Cl:20])=[O:6]

참가 물질

5

반응물 2

HCID 65578Oxalyl chlorideHCID 184644732-methoxy-5-(4H-triazol-4-yl)benzoic acid

생성물 1

HCID 183544512-methoxy-5-(4H-triazol-4-yl)benzoyl chloride

시약·촉매·용매 2

HCID 6228Dimethylformamide촉매HCID 6344Dichloromethane용매

실험 절차

Combine 2-methoxy-5-(4H-triazol-4-yl)benzoic acid (5 mmol) and dichloromethane (40 mL). Add dropwise oxalyl chloride (0.72 mL, 8.25 mmol) followed by dimethylformamide (3 drops). After 4 hours, evaporate invacuo and dry to give the title compound.

후처리

  1. customevaporate invacuo
  2. customdry

출처 및 근거

ORD 기록
ord-2d97fee94ef4490f992404b6f07a9a4a
출처 데이터셋
uspto-grants-2001_10
특허 번호
US06297259B1

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