Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Oxalyl chloride → 2-Methoxy-5-(trifluoromethoxy)benzoyl chloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Oxalyl chloride | HCID 65578 | — |
| 반응물 | 2-methoxy-5-(trifluoromethoxy)benzoic Acid | HCID 2775286 | — |
| 촉매 | Dimethylformamide | HCID 6228 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | 2-Methoxy-5-(trifluoromethoxy)benzoyl chloride | HCID 3580596 | — |
반응 단계
Combine 2-methoxy-5-trifluoromethoxybenzoic acid (0.6 g, 2.53 mmol) and dichloromethane (10 mL). Cool in an ice bath. Add dropwise oxalyl chloride (0.64 mL, 5.0 mmol) followed by dimethylformamide (1 drop). Warm to ambient temperature. After 3 hours, evaporate invcuo and dry to give the title compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06297259B1 |
| 출처 데이터셋 | uspto-grants-2001_10 |
| ORD ID | ord-4614e54603334fb88f3ec6fd29f4d154 |
| 출처 메모 | uspto-grants-2001_10 |