Hydrogen Peroxide → HCID 178507375, 화합물

HRID 379528노트

반응식

HRID 379528 반응식
[NH2:1][C:2]1[C:10]2[N:9]=[N:8][NH:7][C:6]=2[CH:5]=[CH:4][CH:3]=1.[Br-:11].[K+].OO>C(O)(=O)C.[NH4+].[NH4+].[O-][Mo]([O-])(=O)=O>[NH2:1][C:2]1[C:10]2[N:9]=[N:8][NH:7][C:6]=2[C:5]([Br:11])=[CH:4][CH:3]=1

참가 물질

6

반응물 3

HCID 784Hydrogen PeroxideHCID 253877Potassium BromideHCID 178507462HCID 178507462, 화합물

생성물 1

HCID 178507375HCID 178507375, 화합물수율 45.8%

시약·촉매·용매 2

HCID 61578Diammonium molybdate촉매HCID 176Acetic Acid용매

반응 조건

온도
25 °C

실험 절차

To a solution of 4-aminobenzotriazole(550 milligram (hereinafter “mg”), 4.1 mmol) in acetic acid (10 ml) was added potassium bromide (520 mg, 4.4 mmol ), ammonium molybdate(67 mg, 0.55 mmol) and hydrogen peroxide (0.5 ml, 30%). The mixture was stirred at 25° C. for 3 hors. The solvent was evaporated and chromatography of the resulting solid on silica gel (EtOAc/Hexane(1equiv./1equiv.)) gave the desired product(400 mg, 45%). 1H NMR (CD3SO2CD3): δ7.29 (d, 1H), 6.49 (d, 1H), 6.05 (bs, 3H).

후처리

  1. customThe solvent was evaporated

출처 및 근거

ORD 기록
ord-1d8fb6779cd94ac0b03440c435c89267
출처 데이터셋
uspto-grants-2001_10
특허 번호
US06300325B1

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