Bromomethyl 4-methoxyphenyl ketone → 3-Amino-6-chloro-1-ethoxycarbonyl-2-(4-methoxybenzoyl)indole

HRID 379725

반응식

HRID 379725 반응식
[Cl:1][C:2]1[CH:9]=[CH:8][C:5]([C:6]#[N:7])=[C:4]([NH:10][C:11]([O:13][CH2:14][CH3:15])=[O:12])[CH:3]=1.Br[CH2:17][C:18]([C:20]1[CH:25]=[CH:24][C:23]([O:26][CH3:27])=[CH:22][CH:21]=1)=[O:19]>>[NH2:7][C:6]1[C:5]2[C:4](=[CH:3][C:2]([Cl:1])=[CH:9][CH:8]=2)[N:10]([C:11]([O:13][CH2:14][CH3:15])=[O:12])[C:17]=1[C:18](=[O:19])[C:20]1[CH:25]=[CH:24][C:23]([O:26][CH3:27])=[CH:22][CH:21]=1

참가 물질

3

반응물 2

HCID 4965Bromomethyl 4-methoxyphenyl ketoneHCID 183678884-Chloro-2-[(ethoxycarbonyl)amino]benzonitrile

생성물 1

HCID 183677773-Amino-6-chloro-1-ethoxycarbonyl-2-(4-methoxybenzoyl)indole

실험 절차

The title compound was prepared according to the procedure described in step 2 of Example 1 from 4-chloro-2-(ethoxycarbonylamino)benzonitrile (Example 1, step 1) and 2-bromo-4′-methoxyacetophenone.

출처 및 근거

ORD 기록
ord-6c145b5c4c5c41b486add937ff974164
출처 데이터셋
uspto-grants-2001_10
특허 번호
US06300363B1

연결된 노트

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