Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Bromo-1-(3-methylphenyl)ethan-1-one → 3-Amino-6-chloro-2-(3-methylbenzoyl)-1-(ethoxycarbonyl)indole
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Bromo-1-(3-methylphenyl)ethan-1-one | HCID 10036129 | — |
| 반응물 | 4-Chloro-2-[(ethoxycarbonyl)amino]benzonitrile | HCID 18367888 | — |
| 용매 | Ethyl Acetate | HCID 8857 | — |
| 생성물 | 3-Amino-6-chloro-2-(3-methylbenzoyl)-1-(ethoxycarbonyl)indole | HCID 18368043 | — |
반응 단계
The title compound was prepared according to the procedure described in step 2 of Example 1 from 4-chloro-2-(ethoxycarbonylamino)benzonitrile (Example 1, step 1) and 2-bromo-3′-methylacetophenone (R. Yveline, G. Gerard, and M. Geroges, Chem.Pharm.Bull., 1992, 40, 1170.). tlc: Rf=0.5 (25% ethyl acetate in hexanes)
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06300363B1 |
| 출처 데이터셋 | uspto-grants-2001_10 |
| ORD ID | ord-c7cdabc5ada74c36a5184db7236b94a1 |
| 출처 메모 | uspto-grants-2001_10 |