Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Bromo-1-(3-bromophenyl)ethan-1-one → 3-Amino-2-(3-bromobenzoyl)-6-chloro-1-(ethoxycarbonyl)indole
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Bromo-1-(3-bromophenyl)ethan-1-one | HCID 519585 | — |
| 반응물 | 4-Chloro-2-[(ethoxycarbonyl)amino]benzonitrile | HCID 18367888 | — |
| 생성물 | 3-Amino-2-(3-bromobenzoyl)-6-chloro-1-(ethoxycarbonyl)indole | HCID 18367922 | — |
반응 단계
The title compound was prepared according to the procedure described in step 2 of Example 1 from 4-chloro-2-(ethoxycarbonylamino)benzonitrile (Example 1, step 1) and 2-bromo-3′-bromoacetophenone. 1H-NMR (CDCl3) δ: 8.25 (1H, d, J=1.5 Hz), 7.90 (1H, t, J=1.8 Hz), 7.64-7.59 (2H, m), 7.54 (1H, d, J=8.4 Hz), 7.34-7.26 (2H, m), 5.87 (2H, br s). 3.84 (2H, q, J=7.0 Hz), 0.89 (3H, t, J=7.0 Hz)
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06300363B1 |
| 출처 데이터셋 | uspto-grants-2001_10 |
| ORD ID | ord-eced99c4aec24cf48e4af43f977d3a1c |
| 출처 메모 | uspto-grants-2001_10 |