2-Bromo-3'-chloroacetophenone → 3-Amino-2-(3-chlorobenzoyl)-1-(ethoxycarbonyl)-5-nitroindole

반응식

[CH2:1]([O:3][C:4]([NH:6][C:7]1[CH:14]=[CH:13][C:12]([N+:15]([O-:17])=[O:16])=[CH:11][C:8]=1[C:9]#[N:10])=[O:5])[CH3:2].Br[CH2:19][C:20]([C:22]1[CH:27]=[CH:26][CH:25]=[C:24]([Cl:28])[CH:23]=1)=[O:21]>>[NH2:10][C:9]1[C:8]2[C:7](=[CH:14][CH:13]=[C:12]([N+:15]([O-:17])=[O:16])[CH:11]=2)[N:6]([C:4]([O:3][CH2:1][CH3:2])=[O:5])[C:19]=1[C:20](=[O:21])[C:22]1[CH:27]=[CH:26][CH:25]=[C:24]([Cl:28])[CH:23]=1

참가 물질

반응물 2

HCID 387382-Bromo-3'-chloroacetophenone

HCID 183679462-(Ethoxycarbonylamino)-5-nitrobenzonitrile

생성물 1

HCID 183679173-Amino-2-(3-chlorobenzoyl)-1-(ethoxycarbonyl)-5-nitroindole

실험 절차

The title compound was prepared according to the procedure described in step 2 of Example 1 from 2-(ethoxycarbonylamino)-5-nitrobenzonitrile (Example 96, step 1) and 2-bromo-3′-chloroacetophenone.

출처 및 근거

ORD 기록: ord-6600395a89dc4b7586b4b48b4def4808
출처 데이터셋: uspto-grants-2001_10
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06300363B1

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