Trimethylamine → 1,3-Dihydroxy-5-trimethylsiloxyadamantane

HRID 380269

반응식

HRID 380269 반응식
[OH:1][C:2]12[CH2:11][C:6]3([OH:12])[CH2:7][CH:8]([CH2:10][C:4]([OH:13])([CH2:5]3)[CH2:3]1)[CH2:9]2.CN(C)C.[CH3:18][Si:19](Cl)([CH3:21])[CH3:20]>C(Cl)Cl>[OH:1][C:2]12[CH2:11][C:6]3([O:12][Si:19]([CH3:21])([CH3:20])[CH3:18])[CH2:7][CH:8]([CH2:10][C:4]([OH:13])([CH2:5]3)[CH2:3]1)[CH2:9]2

참가 물질

5

반응물 3

HCID 1146TrimethylamineHCID 6397ChlorotrimethylsilaneHCID 98990221,3,5-Adamantanetriol

생성물 1

HCID 219307101,3-Dihydroxy-5-trimethylsiloxyadamantane

시약·촉매·용매 1

HCID 6344Dichloromethane용매

실험 절차

This 1,3,5-trihydroxyadamantane was dissolved in methylene chloride. To this solution were added a small amount of trimethylamine, and then an equimolar amount of trimethylsilyl chloride. Reaction was carried out at room temperature. The reaction product was partitioned by high performance liquid chromatography to obtain 1,3-dihydroxy-5-trimethylsiloxyadamantane.

후처리

  1. customReaction
  2. customwas carried out at room temperature
  3. customThe reaction product was partitioned by high performance liquid chromatography

출처 및 근거

ORD 기록
ord-c1f12315975a4e23b078209576811615
출처 데이터셋
uspto-grants-2001_10
특허 번호
US06303266B1

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