Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-Azido-2-cyanopyridine → 3-Aminopyridine-2-carbonitrile
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-Azido-2-cyanopyridine | HCID 18365075 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 3-Aminopyridine-2-carbonitrile | HCID 577015 | 98.4% |
반응 단계
A solution of 3-azido-2-cyanopyridine (1.44 g, 9.9 mmol) in ethanol (100 ml) was hydrogenated over palladium on carbon (10%, 50 mg) at room temperature and 3.5 p.s.i for 18 h. The catalyst was filtered off over Celite and the filtrate was concentrated to leave the product (1.16 g). 1H NMR (d6-DMSO) 7.87 (1H, d), 7.33 (1H, dd), 7.22 (1H, d), 6.28 (2H, s).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06303613B1 |
| 출처 데이터셋 | uspto-grants-2001_10 |
| ORD ID | ord-a4a17ec38cef4688a38ac0e63cc42f3b |
| 출처 메모 | uspto-grants-2001_10 |