Potassium Carbonate → Benzofuran-7-Carboxylic Acid
반응식
[C:1]([C:5]1[C:13]2[O:12][CH:11]=[CH:10][C:9]=2[CH:8]=[CH:7][CH:6]=1)([O:3]C)=[O:2].C([O-])([O-])=O.[K+].[K+]>CO>[O:12]1[C:13]2[C:5]([C:1]([OH:3])=[O:2])=[CH:6][CH:7]=[CH:8][C:9]=2[CH:10]=[CH:11]1참가 물질
4
실험 절차
A mixture of 0.25 g (0.99 mmol) of 7-Carbomethoxybenzofuran and 0.1 mL of K2CO3 (1N in water) in 6 mL of methanol was stirred at it for 24 h. The reaction mixture was filtered and the filtrate was concentrated. The residue was purified by chromatography (silica, hexanes: ethyl acetate, 4:1, then ethyl acetate: methanol, 9:1) to give 0.15 g of the title compound.
후처리
- filtrationThe reaction mixture was filtered
- concentrationthe filtrate was concentrated
- customThe residue was purified by chromatography (silica, hexanes
출처 및 근거
- ORD 기록
- ord-7f078a8f0ebc43c99f74bb5b3def9a81
- 출처 데이터셋
- uspto-grants-2001_10
- 특허 번호
- US06303593B1
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