1-(1,3-Dioxaindan-5-yl)-2-bromoethan-1-one → HCID 9951334, 화합물

HRID 380566

반응식

HRID 380566 반응식
Br[CH2:2][C:3]([C:5]1[CH:13]=[CH:12][C:8]2[O:9][CH2:10][O:11][C:7]=2[CH:6]=1)=[O:4].[Cl:14][C:15]1[CH:23]=[C:22]2[C:18]([C:19]([CH2:36][C:37]([O:39][CH3:40])=[O:38])=C(C(C3N=CC4CCCCC=4C=3)=O)[NH:21]2)=[CH:17][CH:16]=1>>[O:9]1[C:8]2[CH:12]=[CH:13][C:5]([C:3]([C:2]3[NH:21][C:22]4[C:18]([C:19]=3[CH2:36][C:37]([O:39][CH3:40])=[O:38])=[CH:17][CH:16]=[C:15]([Cl:14])[CH:23]=4)=[O:4])=[CH:6][C:7]=2[O:11][CH2:10]1

참가 물질

3

반응물 2

HCID 2437771-(1,3-Dioxaindan-5-yl)-2-bromoethan-1-oneHCID 9908023methyl [6-chloro-2-[(5,6,7,8-tetrahydroisoquinolin-3-yl)carbonyl]-1H-indol-3-yl]acetate

생성물 1

HCID 9951334HCID 9951334, 화합물

실험 절차

The title compound was prepared according to the procedure described in step 2 of Example 1 from 5-bromoacetyl-1,3-benzodioxole (J.Med. Chem., 1977, 20, 394) and methyl trans-4-chloro-2-[(phenylsulfonyl)amino]cinnamate (Example 1, step 1).

출처 및 근거

ORD 기록
ord-ae9addeab3914caabee7f48187873a82
출처 데이터셋
uspto-grants-2001_10
특허 번호
US06303628B1

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