5-acetyl-1-ethoxycarbonyl-2,3-dihydro-1H-indole → 5-bromoacetyl-1-ethoxycarbonyl-2,3-dihydro-1H-indole

반응식

[C:1]([C:4]1[CH:5]=[C:6]2[C:10](=[CH:11][CH:12]=1)[N:9]([C:13]([O:15][CH2:16][CH3:17])=[O:14])[CH2:8][CH2:7]2)(=[O:3])[CH3:2].[Br:18]CC(C1C=C2C(=CC=1)CCC2)=O>>[Br:18][CH2:2][C:1]([C:4]1[CH:5]=[C:6]2[C:10](=[CH:11][CH:12]=1)[N:9]([C:13]([O:15][CH2:16][CH3:17])=[O:14])[CH2:8][CH2:7]2)=[O:3]

참가 물질

반응물 2

HCID 99915835-acetyl-1-ethoxycarbonyl-2,3-dihydro-1H-indole

HCID 131941252-Bromo-1-(2,3-dihydro-1H-inden-5-yl)ethan-1-one

생성물 1

HCID 154537135-bromoacetyl-1-ethoxycarbonyl-2,3-dihydro-1H-indole

실험 절차

*5-bromoacetyl-1-ethoxycarbonyl-2,3-dihydro-1H-indole was prepared from 5-acetyl-1-ethoxycarbonyl-2,3-dihydro-1H-indole (Y. Ishihara et al., J.Chem.. Soc. Perkin Trans.1, 1992, 3401) according to the procedure for preparing 5-bromoacetylindan described in Example 11.

출처 및 근거

ORD 기록: ord-0faa428d2ebc4c4e8e7e0d0b6be7b28e
출처 데이터셋: uspto-grants-2001_10
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06303628B1

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