methyl [6-chloro-2-[(5,6,7,8-tetrahydroisoquinolin-3-yl)carbonyl]-1H-indol-3-yl]acetate → Methyl [6-chloro-2-[(2-methyl-1,2,3,4-tetrahydroisoquinolin-7-yl)carbonyl]-1H-indol-3-yl]acetate
반응식
Br[CH2:2][C:3]([C:5]1[CH:14]=[C:13]2[C:8]([CH2:9][CH2:10][N:11]([CH3:15])[CH2:12]2)=[CH:7][CH:6]=1)=[O:4].[Cl:16][C:17]1[CH:25]=[C:24]2[C:20]([C:21]([CH2:38][C:39]([O:41][CH3:42])=[O:40])=C(C(C3N=CC4CCCCC=4C=3)=O)[NH:23]2)=[CH:19][CH:18]=1>>[Cl:16][C:17]1[CH:25]=[C:24]2[C:20]([C:21]([CH2:38][C:39]([O:41][CH3:42])=[O:40])=[C:2]([C:3]([C:5]3[CH:14]=[C:13]4[C:8]([CH2:9][CH2:10][N:11]([CH3:15])[CH2:12]4)=[CH:7][CH:6]=3)=[O:4])[NH:23]2)=[CH:19][CH:18]=1참가 물질
3
실험 절차
The title compound was prepared according to the procedure described in step 2 of Example 1 from 7-bromoacetyl-2-methyl-1,2,3,4-tetrahydroisoquinoline* and methyl trans-4-chloro-2-[(phenylsulfonyl)amino]cinnamate (Example 1, step 1).
출처 및 근거
- ORD 기록
- ord-695a516babd64e698d8595af91c31f51
- 출처 데이터셋
- uspto-grants-2001_10
- 특허 번호
- US06303628B1
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