Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
5-Amino-2-chlorobenzoic acid → 5-Amino-2-chloro-N-(2-[tricyclo[3.3.1.13,7]dec-1-yl]ethyl)-benzamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 5-Amino-2-chlorobenzoic acid | HCID 37879 | — |
| 반응물 | 2-(Adamantan-1-yl)ethan-1-amine hydrochloride | HCID 2771138 | — |
| 생성물 | 5-Amino-2-chloro-N-(2-[tricyclo[3.3.1.13,7]dec-1-yl]ethyl)-benzamide | HCID 20670058 | 58% |
반응 단계
Prepared according to the method of Example 14 from 1-adamantaneethylamine hydrochloride (0.105 g) and 5-amino-2-chlorobenzoic acid (0.132 g) and purified by supercritical fluid chromatography eluting with CO2 in ethanol to give the title compound as a white foam (0.094 g).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06303659B2 |
| 출처 데이터셋 | uspto-grants-2001_10 |
| ORD ID | ord-147d5b2cd0b94bcaaf2502b70229f416 |
| 출처 메모 | uspto-grants-2001_10 |