2,5-Dimethylbenzoic acid → 2,5-Dimethyl-N-(2-[tricyclo[3.3.1.13,7]dec-1-yl]ethyl)-benzamide

HRID 380703

반응식

HRID 380703 반응식
Cl.[C:2]12([CH2:12][CH2:13][NH2:14])[CH2:11][CH:6]3[CH2:7][CH:8]([CH2:10][CH:4]([CH2:5]3)[CH2:3]1)[CH2:9]2.[CH3:15][C:16]1[CH:24]=[CH:23][C:22]([CH3:25])=[CH:21][C:17]=1[C:18](O)=[O:19]>>[CH3:15][C:16]1[CH:24]=[CH:23][C:22]([CH3:25])=[CH:21][C:17]=1[C:18]([NH:14][CH2:13][CH2:12][C:2]12[CH2:9][CH:8]3[CH2:7][CH:6]([CH2:5][CH:4]([CH2:10]3)[CH2:3]1)[CH2:11]2)=[O:19]

참가 물질

3

반응물 2

HCID 118922,5-Dimethylbenzoic acidHCID 27711382-(Adamantan-1-yl)ethan-1-amine hydrochloride

생성물 1

HCID 206700562,5-Dimethyl-N-(2-[tricyclo[3.3.1.13,7]dec-1-yl]ethyl)-benzamide수율 86.2%

실험 절차

Prepared according to the method of Example 14 from 1-adamantaneethylamine hydrochloride (0.131 g) and 2.5-dimethylbenzoic acid (0.099 g) to give the title compound as a white solid (0.163 g).

후처리

  1. customPrepared

출처 및 근거

ORD 기록
ord-2fcc3d2d75c94032a435e0571064c660
출처 데이터셋
uspto-grants-2001_10
특허 번호
US06303659B2

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