Pyridine → 2-Propenoic acid, 3-phenyl-, 2,4-dinitrophenyl ester

HRID 380716노트

반응식

HRID 380716 반응식
[C:1](Cl)(=[O:10])[CH:2]=[CH:3][C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1.[N+:12]([C:15]1[CH:20]=[C:19]([N+:21]([O-:23])=[O:22])[CH:18]=[CH:17][C:16]=1[OH:24])([O-:14])=[O:13].N1C=CC=CC=1>CC(C)=O>[C:1]([O:24][C:16]1[CH:17]=[CH:18][C:19]([N+:21]([O-:23])=[O:22])=[CH:20][C:15]=1[N+:12]([O-:14])=[O:13])(=[O:10])[CH:2]=[CH:3][C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1

참가 물질

5

반응물 3

HCID 1049PyridineHCID 14932,4-DinitrophenolHCID 660233-Phenylprop-2-enoyl chloride

생성물 1

HCID 740530652-Propenoic acid, 3-phenyl-, 2,4-dinitrophenyl ester수율 71.6%

시약·촉매·용매 1

HCID 180Acetone용매3회

반응 조건

온도
60 °C

실험 절차

66.64 g (0.4 mole) of cinnamoyl chloride and 300 g of methyl ketone (hereinafter referred to as MEK) were placed in a reaction vessel to be stirred by heating at 60° C. under a nitrogen current. 73.64 g (0.4 mole) of 2,4-dinitrophenol, 50 g of pyridine, and 500 g of MEK were added dropwise to the above reaction vessel using a dropping funnel. After that, reflux stirring was conducted for approximately 20 hours under a nitrogen current. After the completion of the reaction, the precipitate was separated by filtration. The filtrate was concentrated until crystals separated out and poured into methanol. 90 g of light yellow colored needle-like crystals (2,4-dinitrophenyl cinnamate) were yielded.

후처리

  1. customwere placed in a reaction vessel
  2. temperatureAfter that, reflux
  3. stirringstirring
  4. customAfter the completion of the reaction
  5. customthe precipitate was separated by filtration
  6. concentrationThe filtrate was concentrated until crystals
  7. customseparated out and
  8. additionpoured into methanol

출처 및 근거

ORD 기록
ord-e44e1239dfd44606a773c7339484058a
출처 데이터셋
uspto-grants-2001_10
특허 번호
US06303742B1

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