Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Water → {[4-(5-Chloro-1,3-dioxobenzo [c]azolidin-2-yl)-3-methylphenyl]amino}-n-(phenylsulfonimidoyl)carboxamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Water | HCID 962 | — |
| 반응물 | Ammonium nitrate | HCID 22985 | — |
| 반응물 | {[4-(5-Chloro-1,3-dioxobenzo[c]azolidin-2-yl)-3-methylphenyl]-amino}-n-(n-p-methoxybenzylphenylsulfonimidoyl)carboxamide | HCID 20799232 | — |
| 용매 | Ceric ammonium nitrate | HCID 180504 | — |
| 생성물 | {[4-(5-Chloro-1,3-dioxobenzo [c]azolidin-2-yl)-3-methylphenyl]amino}-n-(phenylsulfonimidoyl)carboxamide | HCID 20799234 | — |
반응 단계
To 10 mg (0.016 mmol) of {[4-(5-chloro-1,3-dioxobenzo[c]azolidin-2-yl)-3-methylphenyl]-amino}-N-(N-p-methoxybenzylphenylsulfonimidoyl)carboxamide dissolved in 380 μL of CAN followed by 96 uL of water was added 70 mg (0.13 mmol) of cerric ammonium nitrate. After 20 m, the reaction was complete and purified by RP-HPLC to give 1.8 mg (23%) after lyophilization. ES-MS (M+H)+=469 (Cl).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08524721B2 |
| 출처 데이터셋 | uspto-grants-2013_09 |
| ORD ID | ord-6a4f47f1ec1f44798a5a346e1ea3e31f |
| 출처 메모 | uspto-grants-2013_09 |