Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Benzoyl chloride → N-(2-methyl-4-nitrophenyl)benzamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Benzoyl chloride | HCID 7412 | — |
| 반응물 | 2-Methyl-4-nitroaniline | HCID 7441 | — |
| 용매 | Toluene | HCID 1140 | — |
| 생성물 | N-(2-methyl-4-nitrophenyl)benzamide | HCID 2835288 | 95% |
반응 단계
To a suspension of 2-methyl-4-nitroaniline (0.76 g, 5 mmol) in toluene (25 mL) was added neat benzoyl chloride (0.59 mL, 5.08 mmol). The reaction mixture was refluxed for 16 hr, cooled and filtered to give N-(2-methyl-4-nitrophenyl)benzamide (1.21 g, 95%) as a beige solid. ES-MS (M+H)+=257.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08524721B2 |
| 출처 데이터셋 | uspto-grants-2013_09 |
| ORD ID | ord-cfb21d133e044f9098f617d99185e3d2 |
| 출처 메모 | uspto-grants-2013_09 |