Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Tryptamine → 1-(1,3-benzodioxol-5-yl)-2,3,4,9-tetrahydro-1H-beta-carboline
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Tryptamine | HCID 1150 | — |
| 반응물 | Trifluoroacetic acid | HCID 6422 | — |
| 반응물 | Piperonal | HCID 8438 | — |
| 생성물 | 1-(1,3-benzodioxol-5-yl)-2,3,4,9-tetrahydro-1H-beta-carboline | HCID 201172 | 62.7% |
반응 단계
This product was prepared using the same procedure as for Intermediate 1 with tryptamine (20.0 g, 120 mmol), 3,4-methylenedioxybenzaldehyde (20.6 g, 1.1 equiv.) and TFA (18 mL, 2 equiv.) to give the title compound (22 g, 60%) as white crystals after recrystallization from ethanol.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06306870B1 |
| 출처 데이터셋 | uspto-grants-2001_10 |
| ORD ID | ord-bdbfef5ddda649c9a23eb52eb002f8cb |
| 출처 메모 | uspto-grants-2001_10 |