Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Dimethyl Sulfoxide → 2-Chloro-3-nitrobenzaldehyde
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Dimethyl Sulfoxide | HCID 679 | — |
| 반응물 | Triethylamine | HCID 8471 | — |
| 반응물 | 1-(Bromomethyl)-2-chloro-3-nitrobenzene | HCID 18363045 | — |
| 촉매 | Benzenesulfonic acid, 4-methyl-, silver(1+) salt (1:1) | HCID 85606 | — |
| 생성물 | 2-Chloro-3-nitrobenzaldehyde | HCID 12667713 | 20% |
반응 단계
2-Chloro-3-nitrobenzaldehyde (150 mg, 20%) was prepared by reaction of 1-bromomethyl-2-chloro-3-nitrobenzene (1.0 g, 3.9 mmol) with silver p-toluenesulfonate (1.94 g, 1.75 equiv.) in DMSO in the presence of Et3N (4 mL, 7 equiv.) at rt for 1 hour.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06306870B1 |
| 출처 데이터셋 | uspto-grants-2001_10 |
| ORD ID | ord-01c384dd1916471a9090dc44208be730 |
| 출처 메모 | uspto-grants-2001_10 |