Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-Acetaminobenzyl alcohol → N-(3-formylphenyl)acetamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-Acetaminobenzyl alcohol | HCID 96639 | — |
| 촉매 | Manganese dioxide | HCID 14801 | — |
| 용매 | Toluene | HCID 1140 | — |
| 생성물 | N-(3-formylphenyl)acetamide | HCID 256849 | 93% |
반응 단계
A mixture of N-[3-(hydroxymethyl)phenyl]acetamide (10 g, 60.6 mmol) and MnO2 (7.8 g, 90 mmol) in toluene (250 mL) was refluxed for 29 hr, with addition of more MnO2 (0.7 g, 9 mmol) at 24 hr. The reaction was cooled, filtered through Celite and concentrated in vacuo to give N-(3-formylphenyl)acetamide (9.2 g, 75%). ES-MS (M+H)+=164.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08524721B2 |
| 출처 데이터셋 | uspto-grants-2013_09 |
| ORD ID | ord-608dc77e9c7041d8a6b76f2f2709fde6 |
| 출처 메모 | uspto-grants-2013_09 |