Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methanol → Simvastatin
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methanol | HCID 887 | — |
| 반응물 | HCID 178445512 | HCID 178445512 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | Simvastatin | HCID 54454 | — |
반응 단계
Alternatively, III may be agitated in a mixture of water and an organic solvent, preferably methanol, under high dilution conditions to produce simvastatin in its acid form. Simvastatin acid may be isolated by extraction or crystallization and relactonized to produce simvastatin.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06307066B1 |
| 출처 데이터셋 | uspto-grants-2001_10 |
| ORD ID | ord-fd52504a35e746cd8b8005092cc39f97 |
| 출처 메모 | uspto-grants-2001_10 |