HCID 178445512, 화합물 → Simvastatin

HRID 381711

반응식

HRID 381711 반응식
[CH3:1][CH2:2][C:3]([C:6]([O:8][C@@H:9]1[C@@H:14]2[C@@H:15]([CH2:20][CH2:21][C@H:22]3[O:28][C:26](=[O:27])[CH2:25][C@H:24]([OH:29])[CH2:23]3)[C@@H:16]([CH3:19])[CH:17]=[CH:18][C:13]2=[CH:12][C@H:11]([CH3:30])[CH2:10]1)=[O:7])([CH3:5])[CH3:4].B([O-])[O-].B([O-])[O-]>>[CH3:1][CH2:2][C:3]([C:6]([O:8][C@@H:9]1[C@@H:14]2[C@@H:15]([CH2:20][CH2:21][C@H:22]3[O:28][C:26](=[O:27])[CH2:25][C@H:24]([OH:29])[CH2:23]3)[C@@H:16]([CH3:19])[CH:17]=[CH:18][C:13]2=[CH:12][C@H:11]([CH3:30])[CH2:10]1)=[O:7])([CH3:5])[CH3:4]

참가 물질

3

반응물 2

HCID 178445512HCID 178445512, 화합물2회HCID 178514824HCID 178514824, 화합물

생성물 1

HCID 54454Simvastatin

실험 절차

Alternatively, III may be dissolved in an organic solvent and recirculated over a supported diol or polyol stationary phase to which the boronate moiety of III becomes attached. The organic solution is concentrated to obtain simvastatin.

후처리

  1. concentrationThe organic solution is concentrated

출처 및 근거

ORD 기록
ord-658d7d10b5e145a98d878620a12745a5
출처 데이터셋
uspto-grants-2001_10
특허 번호
US06307066B1

연결된 노트

불러오는 중…