Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2,2,2-Trifluoroethylhydrazine → 4,5-Dichloro-2-(2,2,2-trifluoroethyl)-3(2H)-pyridazinone
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2,2,2-Trifluoroethylhydrazine | HCID 78740 | — |
| 반응물 | Mucochloric Acid | HCID 2771871 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 4,5-Dichloro-2-(2,2,2-trifluoroethyl)-3(2H)-pyridazinone | HCID 13881556 | — |
반응 단계
2,2,2-Trifluoroethylhydrazine (70% solution in water, 35.0 g, 0.307 mol) was treated with mucochloric acid (51.88 g, 0.307 mol) in ethanol (300 mL) and refluxed for 5 hours. The solvent was concentrated in vacuo. The crystals obtained were washed with water and air dried (yield: 50 g; 67.5%). 1H NMR (300 MHz, CDCl3) δ 4.8 (q, J=9 Hz, 2H), 7.85 (s, 1H). MS (DCl-NH3) m/z 264 (M+NH4)+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06307047B1 |
| 출처 데이터셋 | uspto-grants-2001_10 |
| ORD ID | ord-b275da0cabc342c7b5e85ec7bdd06e4d |
| 출처 메모 | uspto-grants-2001_10 |